The Journey of TriBsyn™

CarnoSyn® Brands has always been at the forefront of beta-alanine innovation. Clinical research conducted by CarnoSyn® Brands has revealed the powerful benefits of beta-alanine for muscle endurance and cognitive function. However, the biggest challenge to widespread adoption was paresthesia—the tingling sensation many individuals experienced, especially at higher doses. This harmless sensation often prevented users, particularly seniors and active adults, from staying consistent with beta-alanine supplementation over time.

 

Overcoming Paresthesia: The SR CarnoSyn® Solution

The first major breakthrough was the development of SR CarnoSyn® sustained-release tablets. These tablets provided a solution to the paresthesia problem, delivering beta-alanine in a sustained-release format that eliminated paresthesia while maintaining efficacy. This innovation made it possible for individuals to enjoy the benefits of beta-alanine at the recommended efficacious dosage consistently, without the discomfort of paresthesia.

SR CarnoSyn® sustained-release tablets established the foundation for conducting placebo-controlled studies—a crucial step in validating the efficacy of beta-alanine through rigorous scientific research.

Researchers conducted an array of studies across various fields, from basic science to applied research, confirming the versatility of SR CarnoSyn®. These studies have shown that beta-alanine can be personalized for a wide range of users, demonstrating its potential far beyond traditional athletic performance and strength training.

Meeting the Challenge of Product Diversity

As the market evolved, so did consumer demand. While SR CarnoSyn® tablets were effective, the need for greater product variety and formulation flexibility became apparent. Consumers wanted more options in how they incorporated paresthesia-free beta-alanine into their daily routines.

This is where TriBsyn™ emerged as an innovative solution. With its patent-pending formula and Hydro-Oleo technology, TriBsyn™ offers a versatile powder that is clinically proven to boost the bioavailability of beta-alanine by more than 4 times. In the double-blind, three-way crossover clinical study, TriBsyn™ was shown to effectively eliminate paresthesia at the tested dosage while also requiring significantly less material to provide an efficacious dose.

The fine powder format of TriBsyn™ allows for further formulation flexibility, making it compliant for various product types. This evolution has provided a pathway for meeting the diverse needs of professional athletes and wellness enthusiasts as well as users of fortified and medical foods—including those on GLP-1 therapies who may experience muscle mass loss and decreased physical and cognitive performance. Whether it is increasing carnosine levels, supporting muscle health and vitality, or enhancing cognitive function, TriBsyn™ is tailored to meet the evolving demands of today’s consumers.

Product Claims

Brain Health & Mood Improvement

  • Improves executive functioning, mental clarity and enhances cognitive processing.
  • Supports brain health, cognitive function, and memory.
  • Studies showed improved attention and task focus in adults.
  • Promotes a healthy response to everyday stress.
  • Fosters a more balanced mood and supports a sense of calm.
  • Reduces mental fatigue.

Healthy Immunity Support & Systemic Health

  • Provides multi-system support for the essential structure and function of healthy immunity.
  • Carnosine helps the body’s cells fight oxidative damage.
  • Carnosine chelates heavy metals.
  • Supports healthy blood sugar levels already in the normal range.

Muscle & Bone Health

  • Increases muscle strength, working capacity and function in older adults.
  • Increases carnosine levels in muscle, a powerful antioxidant that supports healthy aging throughout the body.
  • Carnosine benefits bone and joint health through its anti-glycation action.
  • Carnosine can contribute to overall skeletal integrity by directly protecting bone structure and supporting muscle function.

Heart Health

  • Studies showed detoxification by protection from oxidative stress.
  • Carnosine protects against lipid peroxidation in the body.
  • Carnosine helps regulate muscle contractions.
  • Carnosine supports healthy circulation.

The Scientific Evolution of TriBsyn™

1st Patent Issued For
CarnoSyn® Beta-Alanine

17 CarnoSyn®
Clinical Trials Completed

1st Patent Issued For
SR CarnoSyn® Sustained
Release Beta-Alanine

47 Global Patents Issued For CarnoSyn® & SR CarnoSyn®
(14 U.S. + 32 Foreign)

SR CarnoSyn® Receives Self-
Affirmed GRAS Affirmation

CarnoSyn® Receives New
Dietary Ingredient Status
From The FDA And Self-
Affirmed GRAS Status

63 Clinical Trials Completed
For CarnoSyn® &
SR CarnoSyn®

2 Clinical Trials Completed
For TriBsyn™